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Argireline Cosmetics Peptide Acetyl Hexapeptide-8

Products Name  Argireline
CAS No  616204-22-9
INCI Name  Acetyl Hexapeptide-8
Specification  ≥95% (HPLC)
Molecular Weight  889.98 g/mol
Chemical Formula  C₃₄H₆₀N₁₄O₁₂
Appearance  White to off-white lyophilized powder
Solubility  Soluble in water (50 mg/mL), slightly soluble in ethanol
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    Product Description

    Argireline (Acetyl Hexapeptide-8) is a synthetic hexapeptide compound composed of six amino acids linked by peptide bonds and modified with acetylation. As a well-known "Botox-like" peptide, it interferes with the transmission of muscle contraction signals by mimicking the structure of neurotransmitter-related peptides. This reduces the formation of dynamic wrinkles without affecting the normal physiological functions of muscles. Unlike Botox, Argireline works through topical application, offering higher safety, making it a popular anti-wrinkle ingredient in cosmetics. Its molecular structure is stable with good skin permeability, allowing it to effectively act on the area where the dermis connects with muscles.
    Acetyl Hexapeptide-8 is used widely in cosmetics and personal care products for its potential anti-aging properties. It is primarily employed as a topical alternative to Botox, aiming to reduce the appearance of fine lines and wrinkles caused by facial muscle contractions. Acetyl Hexapeptide-8 works by inhibiting the release of neurotransmitters that stimulate muscle contractions, resulting in a temporary relaxation of facial muscles. This peptide is often incorporated into skincare formulations, including serums and creams, targeting specific areas prone to wrinkles, such as the forehead, crow's feet, and frown lines.

    Discover the revolutionary power of Aogebio® Argireline (Acetyl Hexapeptide-8), the gold-standard cosmetic peptide that delivers Botox-like effects without injections. 

    Why Choose Aogebio® Argireline?
    ≥95% Purity (HPLC-verified) – Superior to standard cosmetic-grade peptides
    Clinical Backing – 82% users saw visible reduction in expression lines
    Multi-Format Ready – Stable in serums, creams, & eye gels (pH 5-7)

    Benefits

    Thickeners

    Reducing Dynamic Wrinkles and Expression Lines

    By inhibiting signal transmission at neuromuscular junctions, it relaxes facial expression muscles, reducing dynamic wrinkles caused by repeated contractions. Long-term use can prevent dynamic wrinkles from turning into static ones.
    Actives

    Smoothing Skin Texture

    After reducing muscle contraction intensity, the folds on the skin surface caused by muscle pulling become shallower, making the skin feel finer and smoother—especially effective for improving fine lines around the eyes and mouth.
    Emulsifiers

    Synergistically Enhancing Anti-Aging Effects

    When paired with ingredients like collagen and hyaluronic acid, it can help improve skin elasticity while reducing the potential tightness caused by other anti-aging ingredients.
    Emulsifiers

    Gentle and non-invasive

    As a topical ingredient, it avoids the invasive risks of injectable anti-wrinkle products and has low irritation, making it suitable for long-term use by most skin types.
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    Use

    The typical addition level in cosmetic formulations is 0.05% - 1%, with specific concentrations adjusted based on product positioning: Basic anti-wrinkle products usually contain 0.05% - 0.3%; High-potency anti-wrinkle products targeting obvious dynamic wrinkles can be increased to 0.5% - 1%.

    Applications

    It is commonly used in facial creams, serums, lotions, and masks.
    Applications1
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    Anti-Wrinkle Creams/Lotions

    Suitable for overall facial anti-aging care, especially for people over 25 looking to prevent early aging or over 35 aiming to improve obvious wrinkles.
    Applications3
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    Anti-Wrinkle Serums

    As a core ingredient, they target dynamic wrinkles and are suitable for full-face or local use.
    Applications5
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    Neck Care Products

    Such as neck creams, used to reduce horizontal lines on the neck caused by muscle activity and enhance neck skin firmness.
    storage

    Storage

    Store in a closed container at a dry place at room temperature.

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    Animal Testing

    Not animal tested

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    Vegan

    Does not contain animal-derived components

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    GMO

    No data available

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